Programs
Courses Taught
CHEM 111 Fundamentals of Chemistry ICHEM 350 Forensic Instrumental Analysis
NSCM 499 Divisional Seminar
Education
- B.Sc., Chemistry, University of Puerto Rico
- M.Sc., Chemistry, University of Michigan
- Ph.D., Chemistry/Biochemistry, University of Michigan
Affiliations
- Alfred P. Sloan Foundation Fellow, 2005-2010
Awards
- University of Michigan, Rackham Science Award, 2005
- National Science Foundation Alliances of Graduate Education and Professoriate Travel, 2009
Select Works Published
- Flipping of the ribosomal A- site adenines provides a basis for tRNA selection
Zeng, X.; Chugh, J.; Casiano-Negroni, A.; Al-Hashimi, H.M.; Brooks, C.L., Journal of Molecular Biology, May 2014., - Visualizing transient low- populated structures of RNA
Dethoff E.A.; Petzold, K.; Chugh, J.; Casiano-Negroni, A.; Al-Hashimi, H.M., Nature, 2012, vol. 491, pp: 724-728, - NMR and XAS reveal an inner-sphere metal binding site in the P4 helix of the metallo-ribozyme ribonuclease P
Koutmou, K.S.; Casiano-Negroni, A.; Getz, M. M.; Pazicni, S.; Andrews, A. J.; Penner-Hahn, J. E.; Al- Hashimi, H. M.; and Fierke, C. A, Proceedings of the National Academies of Sciences USA, 2010, vol. 107, pp: 2479-2484, - Characterizing µs-ms Exchange in Labeled and Unlabeled Nucleic Acids by Carbon R1? NMR
Hansen, L.A.; Nikolove, N.E.; Casiano-Negroni, A.; Al-Hashimi, M.H., Journal of the American Chemical Society. Journal of the American Chemical Society, 2009, vol. 131, pp: 3818-3819, - Tryptophan- scanning of the Acetylcholine Receptor’s ?M4 Transmembrane Domain
Díaz-De Leon, R; Otero-Cruz, J.D; Torres-Nuñez, D.A; Casiano, A.; Lasalde-Dominicci, J.A, Channels, 2008, vol. 2, pp: 1-10., - Probing Na+ induced changes in the HIV-1 TAR Conformational Dynamics using NMR Residual Dipolar Couplings: New Insights into the Role of Counterions Ions and Electrostatic Interactions in Adaptive Recognition
Casiano-Negroni, A.; Sun, X; Al-Hashimi, H.M., Biochemistry, 2007, vol. 46, pp: 6525-35, - NMR Studies of RNA Dynamics and Structural Plasticity using NMR Residual Dipolar Couplings
Getz, M.; Sun, X; Casiano-Negroni, A.; Zhang, Q.; Al-Hashimi, H.M., Biopolymers, 2007, vol. 86, pp: 384-402,